Copyrighted by the Institute of Enzymology! Melatonin receptor type 1A-A P51046 Q567Z2 Q804J0 -----------------------PSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCY----GLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTV-SWHFCIA--LGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTI----EQQNSARIRQNTREHPSTAN---------- MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIV--VDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQYDPRVYSCTFEQSASSAY-----TIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTM-FVVFVLFAVCWAPLNF--IGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNNQVKVDSV ---NFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRP--NNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVC-FDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIY---IRLKRR--NNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQ-------------------------------------------- MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQYDP----------RVYSCTFEQSASS----AYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVT------MFVVFVLFAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKKRIVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNQVKVDSV --------------------------------LMALVVLLIVAGNVLVIAAIGRTQRLQTLTNLFITSLACADLVMGLLVVPFGATLVVRGTWLWGSFLCECWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKCYQDPGCCDFVTNRAYAIASSIISFYIPLLIMIFVYLRVYREAKEQIRKIDRCEGRFYGSQEQPQPPPLPQHQPILGNGRASKRKTSRVMAMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRD----LVPDWLFVFFNWLGYANSAFNPIIY-CRSPDFRKAFKRL---LCFPR--------KADRRLHAGGQPAPL------------- MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVL-AIVPNLFVGSLQYDPRVYSCTFEQS-----ASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRV--------------------------------KNDNRPKITPHDVRNFVTMFVVFVLFAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVSVCTARIFFGESSNEAQERLKS--KPSPLLMTNNNQVKVDSV ----------------------PDAVYYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKTISAFMKKWIFGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFLMIIFVWMWSIVWSVGPVFNWGAYVPEGILTSCSFDYLSTDPSTRSFILCMYFCGFMLPIIIIAFCYFNIVMSVSNHEKEMAAMAKRLNAKELRKAQAGASAEMKLAKISMVIITQFMLSWSPYAIIALLAQFGPAEWVTPYAAE----LPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKECEDANDAEEEV-------------------- MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVV-AIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVL-AIVPNLFVGSLQYDPRVYSCTFE----QSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRV----KNDNRPKITPHDVRNFVTM------FVVFVLFAVCWAPLNFIGLAVAISP-ERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRI---VVSVCTARIFFGESSNEAQERLLKSKPSPLMTNNNQVKVDSV -FSNKTGVVRSPFEAPQYYLAEP-WQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIMGVAFTWVMALACAAPPL-VGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQ---LVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLP--YAGVAFYIFTHQGSDFGPIFMTIPAFF-AKTSAVYNPVIYIMMNKQFRN---CMVTTLCCGKNPLGDDEASTTVSKTETSQVAP-------------- MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQYDPRVYSCT--------FEQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTMFVVFVL-FAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVSVCTARIFFG--ESSNEAQERLKSKPSPPLMTNNNQVKVDSV LFANASDAYPSAFPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDR----SLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLC-IALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTA------------------ MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTI--------VVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQYDPRVYSCTFEQSASSAY-----TIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTM-FVVFVLFAVCWAPLN-FIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVSVC---TARIFFGESSNEAQERLKSSKPSPLMTNNNQVKVDSV ---NKTGVVRSPFDYPQYYLAEP-WKYSVLAAYMFLLILLGLPINFMTLYVTIQHKKLRTPLNYILLNLGVCNHFMVLCGFTITMYTSLHGYFVFGQTGCYFEGFFATLGGEIALWSLVVLAIERYIVVCKPMS-NFRFGENHAMMGVAFTWIMALACAVPPLF-GWSRYIPEGMQCSCGVDYYTLKPEVNNESFVIYMFVVHFLIPLIIISFCYGRLVCTVKEAAAQQQESATTQKAEKEVTRMVIIMVIF--FLICWVPYAYV--AFYIFTHQGSEFGPIFMTVPAFF-AKSSAIYNPVIYIMLNKQFR---NCMITTLCCGKNPFGDDDASSAATSKTEATSVSTSQ--------- MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQYDPRVYSCTF--------EQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTMFVVFVLFAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNNQVKVDSV ---NGSAGSEDAQLEPAHISPAIPVIITAVYS--VVF--VVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTT-MPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSL-QFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRIT-------RLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIA--LGYTNSSLNPILYAFLDENFKRCFR-------------------------------------------- MFMNGSSLNSSA-LDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGS--LQYDPRVYSCTFEQSASSAYT-------IAVVFFHFILPIMIVTYCYLRIWVLVIQVR----RRVKNDNRPKITPHDVRNFVTMFVVFVLFAVCWAPLNFIGLAVAI-SPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKKRIVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNQVKVDSV -----------------------PWQFSVLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVANLFMVFGGFTTTLYTSLHAYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIMGLALTW-IMAMACAAAPLVGWSRYIPEGMQCSCGIDYYTSRQEVNNESFVIYMFVVHFTIPLVIIFFCYGQ---LVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVVAFLICWVP--YASVAFYIFTHQGSDFGPIFMTIPSFF-AKSSSIYNPVIYIMMNKQFR---NCMLTTLCCGRNPLGDDEASTTASKTETSQVAP-------------- MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQYDPRVYSCTF--------EQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTMFVVFVL-FAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVSVCTARIFFG--ESSNEAQERLKSKPSPPLMTNNNQVKVDSV --------------------------TAGMGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITLPFRYQSLLTRARARALVCTVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDF--VTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLTGPPRPPSPAPSPSPGPPRPADSLANGRSSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRD----LVPDRLFVFFNWLGYANSAFNPIIY-CRSPDFRKAFQRLL----------------------------------------- MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTV----LAIVPNLFVGSLQYDPRVYS----CTFEQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVK--------------------------------NDNRPKITP------HDVRNFVTMFVVFVLFAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNQVKVDSV ---NGSAFLLAPNRSHAPDHDVTQQRDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDF--FTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGR---TGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDN----LIRKEVYILLNWIGYVNSGFNPLIY-CRSPDFRIAFQELL----------------------------------------- MFMNGSSL----NSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLA----IVPNLFVGSLQYDPRVYS----CTFEQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLV---------------IQVRRRVKNDNRPKITPHDVRN-----------FVTMFVVFVLFAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNQVKVDSV -----------------------PWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNVEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIMGVAFTWVMALACAA-PPLAGWSRYIPEGMQCSCGIDYYTLKPEINNESFVIYMFVVHFAIPMIVIFFCYGQ---LVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWVP--YASVAFYIFTHQGSDFGPIFMTLPAFF-AKSSSIYNPVIYIMMNKQFRN---CMITTLCCGKNPLGDDEASASASKTETSQVAP-------------- MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQYDPRVYSCT--------FEQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTMFVVFVL-FAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVSVCTARIFFG--ESSNEAQERLKSKPSPPLMTNNNQVKVDSV ----------------------PRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFG-NVRFDAKLAIVGIAFSWIWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQS-YMIVLMVTCCIIPLAIIMLCYLQVWLAI----RAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHPLMAA---LPAYF-AKSATIYNPVIYVFMNRQFR------------------------------------------------ MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQY--------DPRVYSCTFEQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTMFVVFVLFA--VCWAPLNFIGLAVAISPERVV-PLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRRREYKRIVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNQVKVDSV ------ALNSSAEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYR-WPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVCAFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRND----DIFRIIMAIVLFFFFS--WVPHQIFTFLDVLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLL----------------------------------------- MFMNGSSLNSSALDPSEQ------ALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAI-YPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQY--DPRVYSCTFE-QSASSAYTIAVVF----FHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTMFVVFVLFAVCWAP---LNFIGLAVAIS--PERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNQVKVDSV -FSNATGVVRSPFEYPQYYLAEP-WQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIMGVAFTWVMALACAA-PPLAGWSRYIPEGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIIIFFCYGQ---LVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWVP--YASVAFYIFTHQGSNFGPIFMTIPAFF-AKSAAIYNPVIYIMMNKQFRN---CMLTTICCGKNPLGDDEASA------------------------ MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQYDPRVYSCT--------FEQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTMFVVFVL-FAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVSVCTARIFFGESSNEAAQERLKSKPSPLMTNNNQVKVDSV ----------------------PRWVYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFG-NVRFDAKLAIVGIAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQS-YMIVLMVTCCITPLSIIVLCYLQVW---LAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPG--YPFHPLMAALPAFF-AKSATIYNPVIYVFMNRQFR------------------------------------------------ MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQY--------DPRVYSCTFEQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTMFVVFVL-FAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRRREYKRIVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNQVKVDSV ------TLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSF-CNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNC--DSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCI-LPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYA-FNADFRKAFSTLL----------------------------------------- MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNA-GNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVL-AIVPNLFV------------GSLQYDPRVYSCTFEQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKIT---------------------------PHDVRNFVTMFVVFVLFAVCWAP---LNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNQVKVDSV --------------------------------LILMVIIPTIGGNTLVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEAMWPLPLVLCPAWLFLDVLFSTASIMHLCAISVDRYIAIKKPIQANQYNSRATAFIKITVVWLISIGIAIP-VPIKGIETDVDNPNNITCVLTKERFGDFMLFGSLAAFFTPLAIMIVTYFLTIHALQKKAYLVKNKPPQRLTWLTVSTVFQR---DETPCSSPEKVAMLDGSRKDKALPNSGDETLMRRTSTIGKKSVQTISNEQRASKVLGIVFFLFLLMWCPFFITNITLVLCDSCNQTTLQMLLEIFV---WIGYVSSGVNPLVYTLFNKTFRDAFGRYIT---------------------------------------- MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSI-FHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQYD---PRVYSCTFEQSASSAYTI--AVVFFHFILPIMIVTY----------CYL--------RIWVLVIQVRRRVKNDNRPKITPHDV---------------------------------------RNFVTMFVVFVLFAVCWAP--LNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNQVKVDSV -----------------EQLFVSPEVFVTLG-------VISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGI--LFI--------IYS-----DSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPF-FLHLIFYIS----CPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEII----------------------------------------- MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIY--PYPLVLTSIFHRGWNLGYMHCQISGFLMGV---SVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQYDPRVYSCTFEQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTMFVVFVLFAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYF-----NSCLNAIVYGVLNQNFRREYKRIVVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNQVKVDSV -----DDLNFTGMPPADEDYSPCMLETETLNKYVVIIAYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALT-LPIWAASKVN-GWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATR--TLTQKRHLVKFVCLGCWGLSMNLSLP-FFLFRQAYHPNNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRTLFKAHMGQKH-----------RAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNNIGRALDATEILGFLHSCLNPIIYAFIGQNFRHGFLKIL----------------------------------------- MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLI-----FTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLL-IWALTVLAIVPNLFVGSLQYDPR-----VYSCTFEQSASSAYTIAVV--FFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTMFVVFVLFAVCWAPLNFIGLAVAISPERVVPLIPEW------LFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNQVKVDSV --------NISSVGPWDGPQYHLAPVWAFRLQAAFMGFVFFVGTPLNAIVLVATLHYKKLRQPLNYILVNVSLGGFLFCIFSVFTVFIASCHGYFLFGRHVCALEAFLGSVAGLVTGWSLAFLAFERYVVICKPFGSIR-FNSKHALMVVLATWIIGIGVSIPPFF-GWSRFIPEGLQCSCGPDWYTVGTKYRSEYYTWFLFIFCFIIPLSLICFSYSQL----LRTLRAVAAQQQESATTQKAEREVSHMVVVMVGSFCLCYVPYAALAMYMVNNRNHGLDLRLVTIPAFFSK--SSCVYNPIIYCFMNKQFR------------------------------------------------ MFMNGSSLNSSALDP--SEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQYDPRVYSCT--------FEQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTMFVVFVLFAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCL-NAIVYGVLNQNFRRREYKRIVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNQVKVDSV --------NISSVGPWDGPQYHIAPVWAFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFSVFPVFVASCNGYFVFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFG-NFRFSSKHALTVVLATWTIGIGVSIPPFF-GWSRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQL----LRALKAVAAQQQESATTQKAEREVSRMVVVMVGSFCVCYVP--YAAFAMYMVNNRNHGLDLRLVTIPSFFSK--SACIYNPIIYCFMNKQFQ---------ACIMKMVCGKAMTDESDTCSSQKTEVST----------- MFMNGSSLNSSALDP--SEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQYDPRVYSCT--------FEQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTMFVVFVL--FAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCL-NAIVYGVLNQNFRREYKRIVVSVCTARIFFGESSNEAQERLKSKPSPLMTTNNNQVKVDSV -----------------------------------FISILAITGNIIVLVILTTSQYKLTVPRFLMCNLAFADLCIGIYLLLIASVDIHTKSQYHNYAIDWQTG-AGCDAAGFFTVFASELSVYTLTAITLERWHTITHAMQLDCKVQLRHAASVMVMGWIFAFAAALFPIFGISSYMKVSICLPMDIDSPLSQLYVMSLLVLN-VLAFVVICGCYIHIYLTV----------RNPNIVSSSSDTRIAKRMAMLIFTDFLCMAPISFF----AISASLKVPLIT--VSKAKILLVLFHPINSCANPFLYAIFTKNFRRDF-FILLSKCGCYEMQAQIYRTETSS-------------------------- MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIY-----PYPLVLTSIFHR---GWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALT-VLAIVPNLFVGSLQYDPRVYSCTFEQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKI--TPHDVRNFVTMFVVFVLFAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYF---NSCLNAIVYGVLNQNFRREYKRIVVSVC-----TARIFFGESSNNEAQERLKSKPSPLMTNNNQVKVDSV MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIF SVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHC QISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLL IWALTVLAIVPNLFVGSLQYDPRVYSCTFEQSASSAYTIAVVFFHFILPI MIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTMFVVFVLFAVC WAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQ NFRREYKRIVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNQVKVDSV