<?xml version="1.0"?>
<CCTOPItem id="P34974" transmembrane="yes" evidence="3D">
	<Copyright>Copyrighted by the Institute of Enzymology!</Copyright>
	<Name>Adrenocorticotropic hormone receptor</Name>
	<CrossRef>
		<UniProt id="ACTHR_BOVIN">
			<AC>P34974</AC>
		</UniProt>
		<PDBTM id="2iqp">
			<Chain id="A"/>
		</PDBTM>
		<PDBTM id="2iqr">
			<Chain id="A"/>
		</PDBTM>
		<PDBTM id="2iqs">
			<Chain id="A"/>
		</PDBTM>
		<PDBTM id="2iqu">
			<Chain id="A"/>
		</PDBTM>
		<PDBTM id="2iqv">
			<Chain id="A"/>
		</PDBTM>
		<PDBTM id="2iqw">
			<Chain id="A"/>
		</PDBTM>
		<TOPDB id="AP01016">
			<Alignment>
				<CrossRefSeq>-----NASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQ-SFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICC-----</CrossRefSeq>
				<OrigSeq>MKHILNLYENINSTARNNSDCPAVILPEEIFFTVSIVGVLENLMVLLAVAKNKSLQSPMYFFICSLAISDMLGSLYKILENVLIMFKNMGYLEPRGSFESTADDVVDSLFILSLLGSICSLSVIAADRYITIFHALQYHRIMTPHRALVILTVLWAGCTGSGITIVTFSHHVPTVIAFTALFPLMLAFILCLYVHMFLLARSHTRRTPSLPK-------ANMRGAVTLTVLLGVFIFCWAPFVLHVLLMTFCPADPYCACYMSLFQVNGVLIMCNAIIDPFIYAFRSPELRVAFKKMVICCNCYQ</OrigSeq>
			</Alignment>
		</TOPDB>
	</CrossRef>
	<Sequence length="297" checkSum="53a2fef4973cf72084939256eedee9f1">
		<Seq>MKHILNLYENINSTARNNSDCPAVILPEEIFFTVSIVGVLENLMVLLAVA
KNKSLQSPMYFFICSLAISDMLGSLYKILENVLIMFKNMGYLEPRGSFES
TADDVVDSLFILSLLGSICSLSVIAADRYITIFHALQYHRIMTPHRALVI
LTVLWAGCTGSGITIVTFSHHVPTVIAFTALFPLMLAFILCLYVHMFLLA
RSHTRRTPSLPKANMRGAVTLTVLLGVFIFCWAPFVLHVLLMTFCPADPY
CACYMSLFQVNGVLIMCNAIIDPFIYAFRSPELRVAFKKMVICNCYQ</Seq>
	</Sequence>
	<Topology numTM="7" reliability="90.5953">
		<Region from="1" to="29" loc="O"/>
		<Region from="30" to="50" loc="M"/>
		<Region from="51" to="58" loc="I"/>
		<Region from="59" to="79" loc="M"/>
		<Region from="80" to="105" loc="O"/>
		<Region from="106" to="126" loc="M"/>
		<Region from="127" to="146" loc="I"/>
		<Region from="147" to="167" loc="M"/>
		<Region from="168" to="173" loc="O"/>
		<Region from="174" to="194" loc="M"/>
		<Region from="195" to="217" loc="I"/>
		<Region from="218" to="239" loc="M"/>
		<Region from="240" to="260" loc="O"/>
		<Region from="261" to="279" loc="M"/>
		<Region from="280" to="297" loc="I"/>
	</Topology>
	<Predictions>
		<Prediction name="HMMTOP">
			<Region from="1" to="29" loc="O"/>
			<Region from="30" to="50" loc="M"/>
			<Region from="51" to="58" loc="I"/>
			<Region from="59" to="79" loc="M"/>
			<Region from="80" to="105" loc="O"/>
			<Region from="106" to="126" loc="M"/>
			<Region from="127" to="146" loc="I"/>
			<Region from="147" to="167" loc="M"/>
			<Region from="168" to="173" loc="O"/>
			<Region from="174" to="194" loc="M"/>
			<Region from="195" to="217" loc="I"/>
			<Region from="218" to="239" loc="M"/>
			<Region from="240" to="260" loc="O"/>
			<Region from="261" to="280" loc="M"/>
			<Region from="281" to="297" loc="I"/>
		</Prediction>
		<Prediction name="Memsat">
			<Region from="1" to="26" loc="O"/>
			<Region from="27" to="50" loc="M"/>
			<Region from="51" to="59" loc="I"/>
			<Region from="60" to="90" loc="M"/>
			<Region from="91" to="95" loc="O"/>
			<Region from="96" to="126" loc="M"/>
			<Region from="127" to="145" loc="I"/>
			<Region from="146" to="166" loc="M"/>
			<Region from="167" to="172" loc="O"/>
			<Region from="173" to="200" loc="M"/>
			<Region from="201" to="218" loc="I"/>
			<Region from="219" to="244" loc="M"/>
			<Region from="245" to="256" loc="O"/>
			<Region from="257" to="279" loc="M"/>
			<Region from="280" to="297" loc="I"/>
		</Prediction>
		<Prediction name="Octopus">
			<Region from="1" to="27" loc="O"/>
			<Region from="28" to="48" loc="M"/>
			<Region from="49" to="60" loc="I"/>
			<Region from="61" to="81" loc="M"/>
			<Region from="82" to="105" loc="O"/>
			<Region from="106" to="126" loc="M"/>
			<Region from="127" to="143" loc="I"/>
			<Region from="144" to="164" loc="M"/>
			<Region from="165" to="174" loc="O"/>
			<Region from="175" to="195" loc="M"/>
			<Region from="196" to="219" loc="I"/>
			<Region from="220" to="240" loc="M"/>
			<Region from="241" to="254" loc="O"/>
			<Region from="255" to="275" loc="M"/>
			<Region from="276" to="297" loc="I"/>
		</Prediction>
		<Prediction name="Philius">
			<Region from="1" to="29" loc="O"/>
			<Region from="30" to="50" loc="M"/>
			<Region from="51" to="58" loc="I"/>
			<Region from="59" to="79" loc="M"/>
			<Region from="80" to="107" loc="O"/>
			<Region from="108" to="130" loc="M"/>
			<Region from="131" to="146" loc="I"/>
			<Region from="147" to="168" loc="M"/>
			<Region from="169" to="175" loc="O"/>
			<Region from="176" to="199" loc="M"/>
			<Region from="200" to="217" loc="I"/>
			<Region from="218" to="241" loc="M"/>
			<Region from="242" to="256" loc="O"/>
			<Region from="257" to="278" loc="M"/>
			<Region from="279" to="297" loc="I"/>
		</Prediction>
		<Prediction name="Phobius">
			<Region from="1" to="29" loc="O"/>
			<Region from="30" to="50" loc="M"/>
			<Region from="51" to="58" loc="I"/>
			<Region from="59" to="79" loc="M"/>
			<Region from="80" to="107" loc="O"/>
			<Region from="108" to="126" loc="M"/>
			<Region from="127" to="146" loc="I"/>
			<Region from="147" to="169" loc="M"/>
			<Region from="170" to="174" loc="O"/>
			<Region from="175" to="200" loc="M"/>
			<Region from="201" to="220" loc="I"/>
			<Region from="221" to="244" loc="M"/>
			<Region from="245" to="255" loc="O"/>
			<Region from="256" to="278" loc="M"/>
			<Region from="279" to="297" loc="I"/>
		</Prediction>
		<Prediction name="Pro">
			<Region from="1" to="31" loc="O"/>
			<Region from="32" to="52" loc="M"/>
			<Region from="53" to="63" loc="I"/>
			<Region from="64" to="84" loc="M"/>
			<Region from="85" to="104" loc="O"/>
			<Region from="105" to="125" loc="M"/>
			<Region from="126" to="145" loc="I"/>
			<Region from="146" to="166" loc="M"/>
			<Region from="167" to="175" loc="O"/>
			<Region from="176" to="196" loc="M"/>
			<Region from="197" to="216" loc="I"/>
			<Region from="217" to="237" loc="M"/>
			<Region from="238" to="257" loc="O"/>
			<Region from="258" to="278" loc="M"/>
			<Region from="279" to="297" loc="I"/>
		</Prediction>
		<Prediction name="Prodiv">
			<Region from="1" to="29" loc="O"/>
			<Region from="30" to="50" loc="M"/>
			<Region from="51" to="61" loc="I"/>
			<Region from="62" to="82" loc="M"/>
			<Region from="83" to="105" loc="O"/>
			<Region from="106" to="126" loc="M"/>
			<Region from="127" to="146" loc="I"/>
			<Region from="147" to="167" loc="M"/>
			<Region from="168" to="175" loc="O"/>
			<Region from="176" to="196" loc="M"/>
			<Region from="197" to="216" loc="I"/>
			<Region from="217" to="237" loc="M"/>
			<Region from="238" to="257" loc="O"/>
			<Region from="258" to="278" loc="M"/>
			<Region from="279" to="297" loc="I"/>
		</Prediction>
		<Prediction name="Scampi">
			<Region from="1" to="29" loc="O"/>
			<Region from="30" to="50" loc="M"/>
			<Region from="51" to="58" loc="I"/>
			<Region from="59" to="79" loc="M"/>
			<Region from="80" to="105" loc="O"/>
			<Region from="106" to="126" loc="M"/>
			<Region from="127" to="147" loc="I"/>
			<Region from="148" to="168" loc="M"/>
			<Region from="169" to="179" loc="O"/>
			<Region from="180" to="200" loc="M"/>
			<Region from="201" to="216" loc="I"/>
			<Region from="217" to="237" loc="M"/>
			<Region from="238" to="250" loc="O"/>
			<Region from="251" to="271" loc="M"/>
			<Region from="272" to="297" loc="I"/>
		</Prediction>
		<Prediction name="ScampiMsa">
			<Region from="1" to="29" loc="O"/>
			<Region from="30" to="49" loc="M"/>
			<Region from="50" to="58" loc="I"/>
			<Region from="59" to="78" loc="M"/>
			<Region from="79" to="105" loc="O"/>
			<Region from="106" to="125" loc="M"/>
			<Region from="126" to="146" loc="I"/>
			<Region from="147" to="166" loc="M"/>
			<Region from="167" to="173" loc="O"/>
			<Region from="174" to="193" loc="M"/>
			<Region from="194" to="219" loc="I"/>
			<Region from="220" to="239" loc="M"/>
			<Region from="240" to="257" loc="O"/>
			<Region from="258" to="277" loc="M"/>
			<Region from="278" to="297" loc="I"/>
		</Prediction>
		<Prediction name="TMHMM">
			<Region from="1" to="29" loc="O"/>
			<Region from="30" to="49" loc="M"/>
			<Region from="50" to="61" loc="I"/>
			<Region from="62" to="84" loc="M"/>
			<Region from="85" to="103" loc="O"/>
			<Region from="104" to="126" loc="M"/>
			<Region from="127" to="146" loc="I"/>
			<Region from="147" to="166" loc="M"/>
			<Region from="167" to="175" loc="O"/>
			<Region from="176" to="198" loc="M"/>
			<Region from="199" to="218" loc="I"/>
			<Region from="219" to="241" loc="M"/>
			<Region from="242" to="255" loc="O"/>
			<Region from="256" to="278" loc="M"/>
			<Region from="279" to="297" loc="I"/>
		</Prediction>
	</Predictions>
	<Constraints>
		<Constraint source="TOPDB" sourceId="AP01016">
			<ConstraintRegion from="8" to="27" loc="O" subId="00000" subSource="2iquA"/>
			<ConstraintRegion from="8" to="29" loc="O" subId="00001" subSource="2iqsA"/>
			<ConstraintRegion from="8" to="29" loc="O" subId="00002" subSource="2iqrA"/>
			<ConstraintRegion from="8" to="30" loc="O" subId="00003" subSource="2iqpA"/>
			<ConstraintRegion from="20" to="29" loc="O" subId="00004" subSource="2iqwA"/>
			<ConstraintRegion from="20" to="29" loc="O" subId="00005" subSource="2iqvA"/>
			<ConstraintRegion from="28" to="48" loc="M" subId="00006" subSource="2iquA"/>
			<ConstraintRegion from="30" to="48" loc="M" subId="00007" subSource="2iqvA"/>
			<ConstraintRegion from="30" to="53" loc="M" subId="00008" subSource="2iqwA"/>
			<ConstraintRegion from="30" to="53" loc="M" subId="00009" subSource="2iqsA"/>
			<ConstraintRegion from="30" to="53" loc="M" subId="00010" subSource="2iqrA"/>
			<ConstraintRegion from="31" to="53" loc="M" subId="00011" subSource="2iqpA"/>
			<ConstraintRegion from="49" to="62" loc="I" subId="00012" subSource="2iqvA"/>
			<ConstraintRegion from="49" to="62" loc="I" subId="00013" subSource="2iquA"/>
			<ConstraintRegion from="54" to="55" loc="I" subId="00014" subSource="2iqwA"/>
			<ConstraintRegion from="54" to="58" loc="I" subId="00015" subSource="2iqsA"/>
			<ConstraintRegion from="54" to="58" loc="I" subId="00016" subSource="2iqrA"/>
			<ConstraintRegion from="54" to="58" loc="I" subId="00017" subSource="2iqpA"/>
			<ConstraintRegion from="56" to="79" loc="M" subId="00018" subSource="2iqwA"/>
			<ConstraintRegion from="59" to="78" loc="M" subId="00019" subSource="2iqrA"/>
			<ConstraintRegion from="59" to="78" loc="M" subId="00020" subSource="2iqpA"/>
			<ConstraintRegion from="59" to="79" loc="M" subId="00021" subSource="2iqsA"/>
			<ConstraintRegion from="63" to="80" loc="M" subId="00022" subSource="2iqvA"/>
			<ConstraintRegion from="63" to="81" loc="M" subId="00023" subSource="2iquA"/>
			<ConstraintRegion from="79" to="105" loc="O" subId="00024" subSource="2iqrA"/>
			<ConstraintRegion from="79" to="105" loc="O" subId="00025" subSource="2iqpA"/>
			<ConstraintRegion from="80" to="105" loc="O" subId="00026" subSource="2iqwA"/>
			<ConstraintRegion from="80" to="105" loc="O" subId="00027" subSource="2iqsA"/>
			<ConstraintRegion from="81" to="103" loc="O" subId="00028" subSource="2iqvA"/>
			<ConstraintRegion from="82" to="102" loc="O" subId="00029" subSource="2iquA"/>
			<ConstraintRegion from="103" to="123" loc="M" subId="00030" subSource="2iquA"/>
			<ConstraintRegion from="104" to="122" loc="M" subId="00031" subSource="2iqvA"/>
			<ConstraintRegion from="106" to="129" loc="M" subId="00032" subSource="2iqwA"/>
			<ConstraintRegion from="106" to="130" loc="M" subId="00033" subSource="2iqsA"/>
			<ConstraintRegion from="106" to="130" loc="M" subId="00034" subSource="2iqrA"/>
			<ConstraintRegion from="106" to="130" loc="M" subId="00035" subSource="2iqpA"/>
			<ConstraintRegion from="123" to="151" loc="I" subId="00036" subSource="2iqvA"/>
			<ConstraintRegion from="124" to="151" loc="I" subId="00037" subSource="2iquA"/>
			<ConstraintRegion from="130" to="144" loc="I" subId="00038" subSource="2iqwA"/>
			<ConstraintRegion from="131" to="144" loc="I" subId="00039" subSource="2iqsA"/>
			<ConstraintRegion from="131" to="144" loc="I" subId="00040" subSource="2iqrA"/>
			<ConstraintRegion from="131" to="144" loc="I" subId="00041" subSource="2iqpA"/>
			<ConstraintRegion from="145" to="166" loc="M" subId="00042" subSource="2iqrA"/>
			<ConstraintRegion from="145" to="167" loc="M" subId="00043" subSource="2iqwA"/>
			<ConstraintRegion from="145" to="168" loc="M" subId="00044" subSource="2iqsA"/>
			<ConstraintRegion from="145" to="168" loc="M" subId="00045" subSource="2iqpA"/>
			<ConstraintRegion from="152" to="171" loc="M" subId="00046" subSource="2iqvA"/>
			<ConstraintRegion from="152" to="171" loc="M" subId="00047" subSource="2iquA"/>
			<ConstraintRegion from="167" to="172" loc="O" subId="00048" subSource="2iqrA"/>
			<ConstraintRegion from="168" to="173" loc="O" subId="00049" subSource="2iqwA"/>
			<ConstraintRegion from="169" to="173" loc="O" subId="00050" subSource="2iqsA"/>
			<ConstraintRegion from="169" to="173" loc="O" subId="00051" subSource="2iqpA"/>
			<ConstraintRegion from="172" to="172" loc="O" subId="00052" subSource="2iqvA"/>
			<ConstraintRegion from="172" to="172" loc="O" subId="00053" subSource="2iquA"/>
			<ConstraintRegion from="173" to="190" loc="M" subId="00054" subSource="2iqvA"/>
			<ConstraintRegion from="173" to="190" loc="M" subId="00055" subSource="2iquA"/>
			<ConstraintRegion from="173" to="197" loc="M" subId="00056" subSource="2iqrA"/>
			<ConstraintRegion from="174" to="198" loc="M" subId="00057" subSource="2iqwA"/>
			<ConstraintRegion from="174" to="198" loc="M" subId="00058" subSource="2iqsA"/>
			<ConstraintRegion from="174" to="198" loc="M" subId="00059" subSource="2iqpA"/>
			<ConstraintRegion from="191" to="219" loc="I" subId="00060" subSource="2iquA"/>
			<ConstraintRegion from="191" to="220" loc="I" subId="00061" subSource="2iqvA"/>
			<ConstraintRegion from="198" to="216" loc="I" subId="00062" subSource="2iqrA"/>
			<ConstraintRegion from="199" to="214" loc="I" subId="00063" subSource="2iqsA"/>
			<ConstraintRegion from="199" to="214" loc="I" subId="00064" subSource="2iqpA"/>
			<ConstraintRegion from="199" to="216" loc="I" subId="00065" subSource="2iqwA"/>
			<ConstraintRegion from="215" to="237" loc="M" subId="00066" subSource="2iqsA"/>
			<ConstraintRegion from="215" to="237" loc="M" subId="00067" subSource="2iqpA"/>
			<ConstraintRegion from="217" to="240" loc="M" subId="00068" subSource="2iqrA"/>
			<ConstraintRegion from="217" to="241" loc="M" subId="00069" subSource="2iqwA"/>
			<ConstraintRegion from="220" to="248" loc="M" subId="00070" subSource="2iquA"/>
			<ConstraintRegion from="221" to="244" loc="M" subId="00071" subSource="2iqvA"/>
			<ConstraintRegion from="238" to="261" loc="O" subId="00072" subSource="2iqsA"/>
			<ConstraintRegion from="238" to="261" loc="O" subId="00073" subSource="2iqpA"/>
			<ConstraintRegion from="241" to="260" loc="O" subId="00074" subSource="2iqrA"/>
			<ConstraintRegion from="242" to="260" loc="O" subId="00075" subSource="2iqwA"/>
			<ConstraintRegion from="245" to="260" loc="O" subId="00076" subSource="2iqvA"/>
			<ConstraintRegion from="249" to="258" loc="O" subId="00077" subSource="2iquA"/>
			<ConstraintRegion from="259" to="279" loc="M" subId="00078" subSource="2iquA"/>
			<ConstraintRegion from="261" to="279" loc="M" subId="00079" subSource="2iqvA"/>
			<ConstraintRegion from="261" to="282" loc="M" subId="00080" subSource="2iqrA"/>
			<ConstraintRegion from="261" to="284" loc="M" subId="00081" subSource="2iqwA"/>
			<ConstraintRegion from="262" to="282" loc="M" subId="00082" subSource="2iqsA"/>
			<ConstraintRegion from="262" to="284" loc="M" subId="00083" subSource="2iqpA"/>
			<ConstraintRegion from="280" to="293" loc="I" subId="00084" subSource="2iqvA"/>
			<ConstraintRegion from="280" to="293" loc="I" subId="00085" subSource="2iquA"/>
			<ConstraintRegion from="283" to="293" loc="I" subId="00086" subSource="2iqsA"/>
			<ConstraintRegion from="283" to="293" loc="I" subId="00087" subSource="2iqrA"/>
			<ConstraintRegion from="285" to="293" loc="I" subId="00088" subSource="2iqwA"/>
			<ConstraintRegion from="285" to="293" loc="I" subId="00089" subSource="2iqpA"/>
		</Constraint>
	</Constraints>
</CCTOPItem>
