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G-protein coupled estrogen receptor 1 B3G515 ------------------------FDYGDATPCQKVNERAFGAQLLPPLYSL-VFVIGLVGNILVVLVLVQYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVFGDAMCKILSGFYYTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPGLYFSKTQWEFTHHTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKILLRRPNEK-----KSKAVRLIFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLD--------LAVQVTEVIAYTHCCVNPVIYAFVGERFRKYLRQLFHRRVA------------------------- MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGLFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILVADSLIEV-FNLNEKYYDYAVLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILATL--LPFTIVQ---TQHTGEVHFCFANVFE---IQWLEVTI-GFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRRQKALRMIVVVVLVFFICWLPENVFISIQLLQG-----TADPSKRTDTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRDKLRLFIKRKASSWSVVYRFCNHTLDLQIPVRSESEV ----------------EEVTTFFDY---DYGAPCHKFDVKQIGAQLLPPLYSL-VFIFGFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNA-MCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTKCQKEDSVYVC-GPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEK----KRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQ---ATQVTETLGMTHCCINPIIYAFVGEKFRS------------------------------------ MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGL-FLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLI-LVADSLIEVFNLNEKYYDYAVLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILATLLPFTIVQTQHTGEVHFCFANVFEIQW------LEVTIGFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRRQKALRMIVVVVLVFFICWLPENVFISIQLLQGTADPSKRTDTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRDDKLRLFIKRKASWSVVYRFCNHTLDLQIPVRSESEV -------------------------------------------IFLPTIYSI-IFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQ-----KRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTV--HKWI---SITEALAFFHCCLNPILYAFLGAKFK------------------------------------- MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGLFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILVADSLIEVFNLNEKYYDYAVLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILATLLPFTIVQTQHTGEVHFC---FAN---VFEIQWLEVTIGFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRRQKALRMIVVVVLVFFICWLPENVFISIQ---LLQGTADPSKRTDTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRRDKLRLFIKRKASWSVVYRFCNHTLDLQIPVRSESEV ------------------------------KAGRHSYIFVMI----PTLYSI-IFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLAS-LPAVIHRNVYFIENTNITVCAFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKISD-IVDTAMPITICI----AYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAK------------------------- MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGLFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADL-ILVADSLIEVFNLNEKYYDYAV-LCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILATLLPFTIVQTQHTGE--------VHFCFANVFEIQWLEVT---IGFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRRQKALRMIVVVVLVFFICWLPENVFISIQLL--QGTADPSKRTDTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRD---KLRLFIKRKASSWSVVYRFCNHTLDLQIPVRSESEV ----------------------------------------IAARLLPPLYSL-VFIFGFVGNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEG-LHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEK----KRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAM--------QVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKH----IAKRFCKCCSIFQQEAPERASS--- MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGLFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILVADSLIEVFNLNEKYYDYAVLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILATLLPFTIVQTQHTGEVHFCFANVF---------EIQWLEVTI-GFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRRQKALRMIVVVVLVFFICWLPENVFISIQLLQ-----GTADPSKRTDTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRDKLRLFIKRKASWSVVYRFCN--HTLDLQIPVRSESSEV -------------------GGDFDNYYGADNQSECEYTDWKSSGALIPAIY-MLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSGAVATAVLW---VLAALLAMPVMVLRTTGDLENTTKVQCYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGL-RKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCI----SYVNSCLNPFLYAFFDPRFRQ------------------------------------ MEEQTTNVIQIYVNGTEQFNASFD-FNITDVKESTDTYEFYIIGLFLSCLYTIFLFPIGFIGNILIL-VVNLNHRERMTIPDLYFVNLAVADLILVAD-SLIEVFNLNEKYYDYAVL-CTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILATLLPFTIVQTQHTGEVH----------FCFANVFEIQWL--------EVTIGFLIPFSIIGLCYSLIVRTLM---RAQKHKGLWPRRQKALRMIVVVVLVFFICWLPENVFISIQLLQGTADPSKRTDTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRDDKLRLFIKRKASWSVVYRFCNHTLDLQIPVRSESEV -----------------------DLNFTGMPPADEDYSPCMLETETLNKYVVIIAYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRT--LTQKRHLVKFVCLGCWGLSMNLSLPFFLFRQAYHPNNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRTLFKA--HMG---QKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNNIGRAL--------DATEILGFLHSCLNPIIYAFIGQNFR------------------------------------- MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTY-----EFYIIGLFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILVADSLIEVFNLNEKYYDYAVLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQH-AKLSCSLIWMASILATLLPFTIVQTQH---TGEVHFCFANVFEIQW------LEVTIGFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRRQKALRMIVVVVLVFFICWLPENV------FISIQLLQGTADPSKRTDTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRRDKLRLFIKRKASWSVVYRFCNHTLDLQIPVRSESEV ----------------------------------------IVGLYLAVCVG------GLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVG--VPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFV---LAQGLGVQPSSETAVAILRFCTALGYV-------NSCLNPILYAFLDENFKACFRKFCCASA-------------------------- MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGLFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILVADSLIEVFNLNEKYYDYA-VLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIW-MASILATLLPFTIVQTQHTGEVHF-CFANVFEIQ--WLEV------TIGFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRR---QKALRMIVVVVLVFFICWLPENVFISIQLLQGTA-DPSKRTDTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRDKLRLFIKRKAASWSVVYRFCNHTLDLQIPVRSESEV ----------------------------------------ITAITIMALYSIVCV-VGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKAL--VTIPETTFQTVSWHFCIALG-------YTNSCLNPVLYAFLDENFKRCFREF------------------------------- MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGLFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILVADSLIEVFNLNEKYYDYA-VLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILATLLPFTIVQTQHTGEVHFCFANVFEIQW-----LEVTI---GFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRR---QKALRMIVVVVLVFFICWLPENVFISIQLLQGTADPSKRTDTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRDKLRLFFIKRKASWSVVYRFCNHTLDLQIPVRSESEV ---------ELLAGGWAAGNASTKCSLTKTG-----FQFY----YLPTVY-ILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVW-ALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNS--PLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASL----NSCVDPILYFLAGDTFRRRLSRATRKSSRRS----------------------- MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGLFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADL--ILVADSLIEVFNLNEKYYDYAVLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILATLLPF-----TIVQTQHTGEVHFCFANVFEIQWLEVTIG-----FLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRRQKALRMIVVVVLVFFICWLPENVFISIQL---LQGTADPSKRTDTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRDKLRLFIKRKASWSSVVYRFCNHTLDLQIPVRSESEV ----------------------------------DSFKYNLNG----AVYSV-VFILGLITNSVSLFVFCFRMKMRSETAIFITNLAVSDLLFVCTLPFKIFYNFNRHWPFGDTLCKISGTAFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCAGVWILVLSGGISASLFSTTNVNNATTTCFEGFSKRVWKTYLSKITIFIEV-VGFIIPLILNVSCSSVVLRTLRKPATLSQIGTNKKKVLKMITVHMAVFVVCFVPYN---SVLFLYALVRSQAITNCFLERFAKIMYPITLCLATL----NCCFDPFIYYFTLESFQK------------------------------------ MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGLFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILVADSLIEVF-NLNEKYYDYAVLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILATLLPFTIVQTQHTGEVHFCFANVFEIQW----------LEVTIGFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRRQKALRMIVVVVLVFFICWLPENVFISIQLLQGTADPSKRTDTTLWH----DYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRDDKLRLFIKRKASWSVVYRFCNHTLDLQIPVRSESEV -----------------------------------------IPVIITAVYSV-VFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFG-DVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAA----------LSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDF------------------------------- MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGLFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILVADSLIE--VFNLNEKYYDYAVLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMAS----ILATLLPFTIVQTQ-HTGEVHFCFANVFEIQW---LEVTI---GFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRR---QKALRMIVVVVLVFFICWLPENVFISIQLLQGTADPSKRTDTTLWHDYPLTGHIVNLA-AFSNSCLNPIIYSFLGETFRDKLRLFFIKRKASWSVVYRFCNHTLDLQIPVRSESEV ------------VASTAAVSSSFKCALTKTG-----FQFY----YLPAVY-ILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDA-MCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTIT-CYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNS--PLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASL----NSCVDPILYFLAGDTFRRRLSR-ATRKAS------------------------- MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGLFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADL--ILVADSLI-EVFNLNEKYYDYAVLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILA--TLLPFTIVQTQHTGEVHFCFANVFE-------IQWLEVTIG-FLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRRQKALRMIVVVVLVFFICWLPENVFISIQL---LQGTADPSKRTDTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRDKLRLFIKRKASSWSVVYRFCNHTLDLQIPVRSESEV -------------------------------------------VFLPIVYTI-VFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHS--RKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMFNYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFLIKSQGQS-----------HVYAL--YIVALCLSTLNSCIDPFVYYFVSHDFRDHAK--------------------------------- MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGLFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILVADSLIEV-FNLNEKYYDYA-VLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSL-IWMASILATLLPFTIVQTQHTGEVHFCFA-NVFEIQ---------WLEVTIG-FLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRRQKALRMIVVVVLVFFICWLPENVFISIQLL----QGTADPSKRTDTTLWHDYPLTGHIVNLAAFS-NSCLNPIIYSFLGETFRDKLRRLFIKRKASWSVVYRFCNHTLDLQIPVRSESEV ---------PLFANASDAYPSAFPSAGANASGPPGARSASSLALAIAITALYSAVCA-VGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGE------LLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAV-VCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTL---VDIDRRDPLVV-----AALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKP--------------------------- MEEQTTNVIQIYVNGTEQFNASFDFNITDV--KESTDTYEFYIIGLFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILV-------ADSLIEVFNLNEKYYDYAVLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIW-MASILATLLPFTIVQTQHTGEVHFCFANVFEIQWLEVTI--------GFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRR---QKALRMIVVVVLVFFICWLPENVFISIQLLQGTADPSKRTDTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRDKLRLFIKRKKASWSVVYRFCNHTLDLQIPVRSESEV ------------VNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSA-VCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGE------LLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTL---VDINRRDPLVV-----AALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCR----------------------------- MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGLFLS--CLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILV-------ADSLIEVFNLNEKYYDYAVLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILATLLPFTIVQTQHTGEVHFCFANVFEIQWLEVTI--------GFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRR---QKALRMIVVVVLVFFICWLPENVFISIQLLQGTADPSKRTDTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRDKLRLFIKKRKASWSVVYRFCNHTLDLQIPVRSESEV -------------------------NLTSAPGNTSLCTRDYKITQVLFPLLYTVLFF-VGLITNGLAMRIFFQIRSKSNF-IIFLKNTVISDLLMILTFPFKI--LSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFIIIA-VFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSL----NACLDPFIYFFLCKSFRNSL---------------------------------- MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTD--TYEFYIIGLFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILVADSLIEVFNLNEKYYDYAVLCTFM----SLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILATLLPFTIVQTQ-HTGEVHFC--FANVFEIQWLEVT-----IGFLIPFSIIGLCYSLIVRTLMRA---QKHKGLWPRRQKALRMIVVVVLVFFICWLPENVFISIQLLQGTADPSKRT-DTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRDKLLRLFIKRKASWSVVYRFCNHTLDLQIPVRSESEV ------------MNGTEGLNFYVPFSNKTGVVRSPFEYPQYYLAEPWQFSVLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVANLFMVFGGFTTTLYTSLHAYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGE-NHAIMGLALTWIMAMACAAAPL-VGWSRYIPEGMQCSCGIDYYTSRQEVNNESFVIYMFVVHFTIPLVIIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVVAFLICWVPYASVAFYIFTHQGS-------------DFGPIFMTIPSFFAKSSSIYNPVIYIMMNKQFRN------------------------------------ MEEQTTNVIQIYVNGTEQFNASFDF-NITDVKESTDTYEFYIIG----LFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILVADSLIEVF--NLNEKYYDYAVLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILATLLPFTIVQTQHTGEVHFCFANV-FEIQWLEVT----------IGFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRRQKA----LRMIVVVVLVFFICWLP-ENVFISIQLLQGTADPSKRTDTTLWHDY-PLTGHIVNLAAFSNSCLNPIIYSFLGETFRDDKLRLFIKRKASWSVVYRFCNHTLDLQIPVRSESEV -------------------------------------------------YTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLTMADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIKTAQANTRKRG-ISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEH-YEKGSVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAVFIICFVPHHV---VQLPWTLAELGFQDSK--FHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHL---------------------------------- MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGLFLSCLYTIF------LFPIGFIGN--ILILVVNLNHRERMTIPDLYFVNLAVADLI-LVADSLIEVFNLNEKYYDYA-VLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILATLLPFTIVQTQHT-------GEVHFCFANVFEIQWLEVTI-------GFLIPFSIIGLCYSLIVRT-LMRAQKHKGLWPRRQKALRMIVVVVLVFFICWLPENVFISIQLLQGTADPSKRTDTTLWHDYPLTGHIVNLAAFSNSC-LNPIIYSFLGETFRDKLLRLFIKRKASWSVVYRFCNHTLDLQIPVRSESEV ------------MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGE-NHAIMGVAFTWVMA-LACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGS-------------DFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRN------------------------------------ MEEQTTNVIQIYVNGTE--QFNASFDFNITDVKESTDTYEFYIIGLF---LSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILVADSLIEVF--NLNEKYYDYAVLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILATLLPFTIVQTQHTGEVHFCFANVFEIQWLEVT-----------IGFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRRQKA----LRMIVVVVLVFFICWLP-ENVFISIQLLQGTADPSKRTDTTLWHDY-PLTGHIVNLAAFSNSCLNPIIYSFLGETFRDDKLRLFIKRKASWSVVYRFCNHTLDLQIPVRSESEV -------------NGTGQ--------ALGLPPTTCVYRENFKQLLLPPVYSAVLA-AGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFA--CRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLA-VTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPG-------VPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAKWQ----------------------- MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGLFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILVADSLIEVFNLNE----KYYDYAVLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAK-LSCSLIWMASILATLLP---FTIVQTQHTGEVHF-----CFANVFEIQWLEVT-IGFLIPFSIIGLCYSLIVRTLMR--AQKHKGLWPRRQKALRMIVVVVLVFFICWLP----ENVFISIQLLQGTADPSKRTDTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRDKL-RLFIKRKASWSSVVYRFCNHTLDLQIPVRSESEV ------------MNGTEGPNFYVPFSNKTGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTT--TLYTSLHGYFVFGPTGCNVEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGE-NHAIMGVAFTWVMALACAAPPLAGWSRYIPEGMQCSCGIDYYTLK-PEINNESFVIYMFVVHFAIPMIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWVPYASVAFYIFTHQGS-------------DFGPIFMTLPAFFAKSSSIYNPVIYIMMNKQFRN------------------------------------ MEEQTTNVIQIYVNGTEQFNASFDF-NITDVKESTDTYEFYIIG----LFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILVADSLIEVFNLNEKYYDYAVL----CTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIW-MASILATLLPFTIVQTQHTGEVHFCFANVFEIQWLEVT----------IGFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRRQKA----LRMIVVVVLVFFICWLP-ENVFISIQLLQGTADPSKRTDTTLWHDY-PLTGHIVNLAAFSNSCLNPIIYSFLGETFRDDKLRLFIKRKASWSVVYRFCNHTLDLQIPVRSESEV ------------MNGTEGPNFYIPMSNKTGVVRSPFDYPQYYLAEPWKYSVLAAYMFLLILLGLPINFMTLYVTIQHKKLRTPLNYILLNLGVCNHFMVLCGFTITMYTSLHGYFVFGQTGCYFEGFFATLGGEIALWSLVVLAIERYIVVCKPMSNFRFGE-NHAMMGVAFTWIMA-LACAVPPLFGWSRYIPEGMQCSCGVDYYTLKPEVNNESFVIYMFVVHFLIPLIIISFCYGRLVCTVKEAAAQQQESATTQKAEKEVTRMVIIMVIFFLICWVPYAYVAFYIFTHQGS------------EFGPIFMTVPAFFAKSSAIYNPVIYIMLNKQFRN------------------------------------ MEEQTTNVIQIYVNGTEQFNASFDF-NITDVKEST-DTYEFYIIGLFLSCLYTIFLFPIGFIG---NILILVVNLNHRERMTIPDLYFVNLAVAD--LILVADSLIEVFNLNEKYYDYAVLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILATLLPFTIVQTQHTGEVHFCFANV-FEIQWLEVT----------IGFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRRQKA----LRMIVVVVLVFFICWLP-ENVFISIQLLQGTADPSKRTDTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRDDKLRLFIKRKASWSVVYRFCNHTLDLQIPVRSESEV ---------------------------------------------LTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDA-KLAIVGIAFSWIWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACF----AAANPG-------YAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKK---------------------------- MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGLFLSCLYTIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLI-LVADSLIEVFNLNEKYYDYA-VLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSSSPLRTMQHAKLSCSLIWMASILATLLP-FTIVQTQHTGEVHFCFANVFEIQWLEVTIGFLI---------PFSIIGLCY---SLIVRTLMRAQKHKGLWPRRQKAL-RMIVVVVLVFFICWLPENVFISIQLLQGTADPSKRTDTTLWHDYPLTGHIVNLAAFSNSCLNPIIYSFLGETFRDK-LRLFIKRRKASWSVVYRFCNHTLDLQIPVRSESEV MEEQTTNVIQIYVNGTEQFNASFDFNITDVKESTDTYEFYIIGLFLSCLY TIFLFPIGFIGNILILVVNLNHRERMTIPDLYFVNLAVADLILVADSLIE VFNLNEKYYDYAVLCTFMSLFLQVNMYSSIFFLTWMSFDRYVALTSSMSS SPLRTMQHAKLSCSLIWMASILATLLPFTIVQTQHTGEVHFCFANVFEIQ WLEVTIGFLIPFSIIGLCYSLIVRTLMRAQKHKGLWPRRQKALRMIVVVV LVFFICWLPENVFISIQLLQGTADPSKRTDTTLWHDYPLTGHIVNLAAFS NSCLNPIIYSFLGETFRDKLRLFIKRKASWSVVYRFCNHTLDLQIPVRSE SEV